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Updated Sim-e-Child's Publications list

The partners of Sim-e-Child published 25 articles in Scientific Journals as a result of funding, or partial funding from the European Commission. 

  1. Amodeo A., Brancaccio G., Michielon G., Filippelli S., Ricci Z., Morelli S., Gagliardi MG., Iacobelli R., Pongiglione G., Di Donato RM., Pneumatic pulsatile ventricular assist device as a bridge to heart transplantation in pediatric patients, Artif Organs. 2010 Nov;34(11):1017-22.
  2. Barcudi S., Sanders SP., Di Donato RM., de Zorzi A., Iacobelli R., Amodeo A., Gagliardi MG., Borgia F., Pongiglione G, Rinelli G., Aberrant left innominate artery from the left descending aorta in right aortic arch: echocardiographic diagnosis, J Am Soc Echocardiogr. 2010 Feb;23(2):221.e5-7.
  3. Brancaccio G., Amodeo A., Ricci Z., Morelli S., Gagliardi MG., Iacobelli R., Michielon G., Picardo S., Parisi F., Pongiglione G., Di Donato RM., Mechanical assist device as a bridge to heart transplantation in children less than 10 kilograms, Ann Thorac Surg. 2010 Jul;90(1):58-62.
  4. Carotti A., Albanese SB., Filippelli S., Ravà L., Guccione P., Pongiglione G., Di Donato R.M., Determinants of outcome after surgical treatment of pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries, J Thorac Cardiovasc Surg. 2010 Nov;140(5):1092-103.
  5. Carotti A., Albanese S.B., Filippelli S., Ravà L., Guccione P., Pongiglione G., Di Donato R.M., Determinants of outcome after surgical treatment of pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries, J Thorac Cardiovasc Surg. 2010 Nov
  6. Cavallini M., Di Zazzo G., Giordano U., Pongiglione G., Dello Strologo L., Capozza N., Emma F., Matteucci M.C., Long-term cardiovascular effects of pre-transplant native kidney nephrectomy in children, Pediatr Nephrol. 2010 Dec;25(12):2523-9.
  7. Comaniciu, D., Patient-Specific Modelling of Whole Heart Anatomy, Dynamics and Hemodynamics from 4D cardiac CT Images, Interface Focus 2010 - (invited publication-submitted)
  8. De Caro E., Smeraldi A., Trocchio G., Calevo M., Hanau G., Pongiglione G., Subclinical cardiac dysfunction and exercise performance in childhood cancer survivors, Pediatr Blood Cancer. 2011 Jan;56(1):122-6.
  9. De Caro E., Spadoni I., Crepaz R., Saitta M., Trocchio G., Calevo M.G., Pongiglione G., Stenting of aortic coarctation and exercise-induced hypertension in the young, Catheter Cardiovasc Interv. 2010 Feb 1;75 (2):256-61. Erratum in: Catheter Cardiovasc Interv. 2010 Jun 1;75 (7):1143.
  10. Everett, A., Development and validation of a novel automated learning based algorithm for quantification of MRI right ventricular volume in Tetralogy of Fallot, submitted abstract for the 45th Annual Meeting of the Association of European Paediatric Cardiology, to be held in Granada, Spain in May 2011.
  11. Gagliardi M.G., Papavasileiou L., Pongiglione G., Rescue treatment by percutaneous closure of interatrial septal defect or PFO in infants with berlin heart, Catheter Cardiovasc Interv. 2010 Sep 17
  12. Gagliardi M.G., Papavasileiou L., Pongiglione G., Rescue treatment by percutaneous closure of interatrial septal defect or PFO in infants with Berlin heart, Catheter Cardiovasc Interv. 2011 March
  13. Grbic S., Ionasec R., Vitanovski D. ,  Voigt I., Georgescu B.,  Navab N.,  Comaniciu D., Complete Valvular Heart Apparatus Model from 4D Cardiac CT, Medical Image Computing and Computer Assisted Intervention (MICCAI), Beijing, China, September 20-24 2010.
  14. Ionasec R., Georgescu B., Navab N., Comaniciu D., Patient-Specific Modelling of Whole Heart Anatomy, Dynamics and Hemodynamics from 4D cardiac CT Images, BMT – 2010, Rostock2010
  15. Ionasec R., Suehling M., Comaniciu D., Sim-e-Child: Grid-Enabled Platform for Simulations in Paediatric Cardiology Toward the Personalized Virtual Child Heart – VPH NoE 2010
  16. Leonardi B., Vitanovski D., Everett A., Spevak Ph.,  Suehling M., Razvan I.,  Mantione L.,  Pongiglione G., Automatical patient-specific 3D aortic arch model estimation for patient treatment with aortic arch anomalies, Journal of cardiovascular magnetic resonance, 14(Suppl 1): O56, February 2012.
  17. Mihalef V., Ionasec R.I., Sharma P., Georgescu B., Huber M., Comaniciu, D., Patient-Specific Modelling of Whole Heart Anatomy, Dynamics and Hemodynamics from 4D cardiac CT Images, Virtual Physiological Human Conference 2010, Brussels 2010.
  18. Mihalef V., Ionasec R.I., Georgescu G., Voigt I., Suehling M., Comaniciu D., Patient-specific modelling of whole heart anatomy, dynamics and haemodynamics from four-dimensional cardiac CT images, Royal Society Interface Focus Journal, June 6, 2011.
  19. Ralovich K., Mihalef V., Sharma P. , Itu L., Vitanovski D., Ionasec R., Suehling M., Everett A., Pongiglione G., Navab N., and Comaniciu D., Modeling and Simulation Framework for Hemodynamic Assessment of Aortic Coarctation Patients, ISMRM 2012
  20. Ralovich K., Ionasec R. I., Mihalef V., Georgescu B., Everett A., Navab N., and Comaniciu D., Computational Fluid Dynamics Framework for Large-Scale Simulation in Pediatric Cardiology, in Computational Biomechanics for Medicine VI (CBM6), MICCAI Workshop, 2011.
  21. Tuo G., Volpe P., Bondanza S., Volpe N., Serafino M., De Robertis V., Zannini L., Pongiglione G., Calevo MG., Marasini M., Impact of prenatal diagnosis on outcome of pulmonary atresia and intact ventricular septum, J Matern Fetal Neonatal Med. 2011 Jun
  22. Voigt I., Mansi T., Mihalef V., Ionasec R.I.,  Calleja A., Mengue A.,  Sharma P.,  Houle H.,  Georgescu B.,  Hornegger J.,  Comaniciu D., Patient-Specific Model of Left Heart Anatomy, Dynamics and Hemodynamics from 4D TEE: A First Validation Study, Sixth International Conference on Functional Imaging and Modeling of the Heart, FIMH 2011, May 25-27, 2011.
  23. Vitanovski D., Ionasec R.I., Tsymbal A., Georgescu B.,  Huber M., Hornegger J.,  Comaniciu D., Cross-modality Assessment and Planning for Pulmonary Trunk Treatment using CT and MRI imaging, Medical Image Computing and Computer Assisted Intervention (MICCAI), Beijing, China, September 20-24 2010.
  24. Vitanovski D., Tsymbal A., Ionasec A., Greiser A., Schmidt M., Mueller E., Lu X., Funka-Lea G., Hornegger J., Comaniciu D., Accurate Regression-based 4D Mitral Valve Surface Reconstruction from 2D+t MRI Slices, in Machine Learning in Medical Imaging, MICCAI Workshop 2011.
  25. Vitanovski D., Ralovich K.,  Ionasec R.I., Zheng Y.,  Suehling M., Krawtschuk W., Hornegger J. and Comaniciu D., Personalized Learning-based Segmentation of Thoracic Aorta and Main Branches for Diagnosis and Treatment Planning, ISBI 2012.



The following table provides a selection of publications that were produced during the Health-e-Child project which built the necessary models and distributed computing environment that Sim-e-Child is building on. Not all of the papers were produced by member of the Sim-e-Child consortium, for more information on these papers and the work of Health-e-Child please go to www.health-e-child.org.


Title of Publication


Publication “Health-e-Child” booklet for: Resource book of eHealth 
projects Sixth Research and Development Framework Programme 


Paper submitted and accepted at annual HealthGrid conference, 
Valencia (E), June 6-9, 2006: “Health-e-Child: An Integrated 
Biomedical Platform for Grid-Based Paediatrics”. (Authors: Jörg 
Freund, Dorin Comaniciu, Yannis Ioannidis, Peiya Liu, Richard 
McClatchey, Edwin Morley- Fletcher, Xavier Pennec, Giacomo 
Pongiglione and Xiang Zhou.)


Paper submitted and accepted at OnToContent Workshop 2006, 
Montpellier (F) - 31/10/2006 “The Management and Integration of
Biomedical Knowledge in a Grid Architecture: Application in the 
Health-e-Child Project.” 
(authors: E. Jimenez-Ruiz, R. Berlanga, 
I. Sanz, R. McClatchey, R. Danger, D. Manset, J. Paraire, A. Rios.)


Major write-up published in “Medical Solutions: Changing the Way 
Healthcare is Delivered” periodical magazine of Siemens Medical 
Solutions distributed during RSNA 2006, annual conference of the 
Radiology Society of North America (Chicago, 26/11 - 1/12 2006)


Circulation 2008; 117(15):1964-72 "Percutaneous pulmonary valve 
implantation: impact of evolving technology and learning curve on 
clinical outcome"  (Authors: Lurz P., Coats L., Khambadkone K., 
Nordmeyer J., Boudjemline Y., Schievano S., Muthurangu V., Yen 
Lee T., Parenzan G., Derrick G., Cullen S., Walker F., Tsang V., 
Deanfield J., Taylor A.M., Bonhoeffer P.)


EHJ 2008; 29(6):810-5 "Percutaneous pulmonary valve-in-valve 
implantation: a successful treatment concept for early device f
ailure in transcatheter"  (Authors: Nordmeyer, J., Coats, L., Lurz, 
P, Lee, T.-Y., Rees, P., Cullen, S., Taylor, A.M., Khambadkone, S.
, Bonhoeffer, P.)


Eur J Cardiothorac Surg 2008; 34(3): 576-580 "Current 
approaches to pulmonary regurgitation"  (Authors: Frigiola A., 
Tsang V.T., Nordmeyer J., Lurz P., van Doorn C., Taylor A.M., 
Bonhoeffer P., de Leval M.)

February 2008

Modélisation électromécanique du coeur et analyse d'images” in 
Proc of Congres des Socitetes Francaises Medico-Chirurgicales 
Pediatriques, Nantes, France. Archives de Pédiatrie 15(5):1032 - 
Mansi, T., Sermesant, M., Huber, M., Taylor, A., Pongiglionne, G., 
Pennec, X., Boudjemline, Y.www.sop.inria.fr/asclepios/biblio/REP/

Spring 2010

Accepted and camera-ready version submitted to be published in: 
H.R. Arabnia (ed.), Advances in Computational Biology, (to appear)
"Discriminative distance functions and the patient neighbourhood 
graph for clinical decision support" (Authors: Tsymbal, A., Huber, M., 
Zhou, S.K.) Link: http://www.sciencedirect.com/science/book/

June 2008

Medical Informatics Europe (MIE). 21st Congress of the European 
Federation for Medical Informatics "Visualization of Patient Proximity 
in Medical Case-Based Reasoning Systems"  (Authors: Tsymbal, A.
, Vitanovski, D., Mircean, C., Lynch, M., Huber, M.)

June, 2008

Proceedings of the 21st IEEE International Symposium on Computer
-Based Medical Systems (CBMS 2008). pp 644-649 ISBN 978-0-7695
-3165-6 ISSN 1063-7125., University of JyvŠskylä, Finland. "Medical 
Data Integration and the Semantic Annotation of Medical Protocols 
(Authors: Berlanga, R., Jimenez-Ruiz, E., Nebot, V., Manset, D., 
Branson, A., Hauer, T., McClatchey, R., Rogulin, D., Shamdasani, 
J., Zillner, S. and Freund, J.) Link: http://ieeexplore.ieee.org/xpl/fre


Ionasec, R. I., Georgescu, B., Gassner, E., Vogt, S., Kutter, O., 
Scheuering, M., Navab, N., and Comaniciu, D., Dynamic model
-driven quantication and visual evaluation of the aortic valve 
from 4D CT; in International Conference on Medical Image 
Computing and Computer-Assisted Intervention (MICCAI)], 2008

October 2008

"An Architecture for Semantic Navigation and Reasoning with Patient 
Data - Experiences of the Health-e-Child Project "  (Authors: Hauer,  
Tamás; Rogulin, Dmitry; Zillner, Sonja; Branson, Andrew; Shamdasani, 
Jetendr; Tsymbal, Alexey; Huber, Martin; Solomonides, Tony  
and  McClatchey, Richard) Lecture Notes in Computer Science Vol 
5318, pp 737-750 Springer 2008, ISBN 978-3-540-88563-4. 
(Proceedings of the 7th International Semantic Web Conference 
(ISWC 2008) Karlsruhe, Germany.)
Link: http://www.springerlink.com/content/c806q566750l1155  

November 2008

Y. Zheng, A. Barbu, B. Georgescu, M. Scheuering, D. Comaniciu:
Four-Chamber Modeling and Anatomic Segmentation for 3D 
Cardiac CT Volumes using Marginal Space Learning and 
Steerable Features, IEEE Trans. Medical Imaging, Vol. 27, No. 11
, 1668-1681, 2008


Y. Zheng, B. Georgescu, H. Lingm S.K. Zhou, M. Scheuering, D. 
Comaniciu: Constrained Marginal Space Learning for Efficient 3
D Anatomical Structure Detection in Medical Images, IEEE Int’l 
Conf. Computer Vision and Pattern Recognition, Miami, Florida, 


Voigt, R. Ionasec, B. Georgescu, H. Houle, M. Huber, J. Hornegger
, D. Comaniciu: Model-Driven Physiological Assessment of the 
Mitral Valve from 4D TEE, SPIE Medical Imaging, Orlando, FL, 2009


Circulation 2009; 119(23):2995-3001 "Comparison of bare metal 
stenting and PPVI for treatment of RVOT obstruction: Utilization of 
an X-ray/MR hybrid lab for acute physiological comparison" (Authors: 
Lurz, P., Nordmeyer, J., Muthurangu, V., Khambadkone, S., Derrick, 
G., Yates, R., Sury, M., Bonhoeffer, P., Taylor, A.M.)


EHJ 2009; 30(17):2147-54 "Quantitative assessment of homograft 
function one year after insertion into pulmonary position - Impact of 
in-situ homograft geometry on valve competence"  (Authors: 
Nordmeyer, J., Tsang, V., Gaudin, R., Lurz, P., Frigiola, A., Jones, A., 
Schievano, S., van Doorn, C., Bonhoeffer, P, Taylor, A.M.)


EHJ 2009; 30(18):2266-74 "Improvement in bare metal stenting 
filling properties after relief of right ventricle to pulmonary artery 
conduit obstruction - contribution of septal motion and 
interventricular mechanical delay"  (Authors: Lurz, P., Puranik, R.
, Nordmeyer, J., Muthurangu, V., Hansen, M.S., Schievano, S., 
Marek, J., Bonhoeffer, P., Taylor, A.M.)


-Lurz P, Puranik R, Nordmeyer J, Muthurangu V, Hansen MS, 
Schievano S, Marek J, Bonhoeffer P, Taylor AM. Improvement in 
left ventricular filling properties after relief of right ventricle to 
pulmonary artery conduit obstruction - contribution of septal motion 
and interventricular mechanical delay. EHJ 2009; 30(18):2266-74


Heart 2009; 95(8):646-50 "Immediate clinical and haemodynamic 
benefits of restoration of pulmonary valvar competence in patients 
with pulmonary hypertension"  (Authors: Lurz, P., Nordmeyer, J., 
Coats, L., Taylor, A.M., Bonhoeffer, P., Schulze-Neick, I.)


Published in Journal of Magnetic Resonance Imaging; http://www3
  "Feasibility and 
reproducibility of biventricular volumetric assessment of cardiac
function during exercise using real-time radial k-t SENSE magnetic 
resonance imaging"  (Authors: Lurz, Philipp; Muthurangu, Vivek; 
Schievano, Silvia;  Nordmeyer, Johannes; Bonhoeffer, Philipp;  
Taylor, Andrew M.;  Hansen, Michael S. PhD)
 Link: http://www3.interscience.wiley.com/journal/122351959/abstrac


Lurz P, Bonhoeffer P, Taylor AM. Percutaneous pulmonary valve 
implantation: an update. Expert Review of Cardiovascular Therapy 
2009: 7(7):823-33


R. Ionasec, Y. Wang, B. Georgescu, I. Voigt, N. Navab, D. Comaniciu: 
Robust Motion Estimation using Trajectory Spectrum Learning: 
Application to Aortic and Mitral Valve Modeling from 4D TEE, IEEE 
Int’l Conf. Computer Vision and Pattern Recognition, Kyoto, Japan, 

Jan 2009

R. Ionasec, A. Tsymbal, D. Vitanovski, B. Georgescu, S.K, Zhou, N.
Navab, D. Comaniciu: Shape-Based Diagnosis of the Aortic Valve, 
SPIE Medical Imaging, Orlando, FL, 2009. 

Jan 2009

Y. Zheng, X. Lu, B. Georgescu, A. Littmann, E. Mueller, D. Comaniciu: 
Automatic Left Ventricle Detection in MR Images Using Marginal 
Space Learning and Component-Based Voting, SPIE Medical Imaging

February 2009

JTCVS 2009; 138(1):84-8 "Effective trans-catheter valvulation of 
pulmonaryhomograft failure-a new perspective to the Ross operation" 
(Authors: Nordmeyer, J., Lurz, P., Tsang, V., Coats, L., Walker, F., 
Taylor, A.M., Khambadkone, S., Bonhoeffer, P.)

May 2009

Advances in Computational Mathematics "c for L_r-convergence of 
empirical processes"  (Authors: Caponnetto, A., De Vito, E., Pontil, M.)

May 2009

J Magn Reson Imaging 2009; 29(5):1062-1070 "Feasibility and 
reproducibility of biventricular volumetric assessment of cardiac 
function during exercise using real-time radial k-t SENSE magnetic 
resonance imaging"  (Authors: Lurz P., Muthurangu V., Schievano S., 
Nordmeyer J., Bonhoeffer P., Taylor A.M., Hansen M.S.)


Heart 2010; 96:304-308 "Longterm Functional Outcomes After the 
Ross (Pulmonary Autograft) Procedure"  (Authors: Puranik, R., 
Tsang, V.T., Broadley, A., Nordmeyer, J., Lurz, P., Muthialu, N., 
Derrick, G., Walker, F., Cullen, S., de Leval, M., Bonhoeffer, P., 
Taylor, A.M., Muthurangu, V.)


Y. Zheng, B. Georgescu, D. Comaniciu: Anatomical Structures in 
Medical Images, Information Processing in Medical Imaging (IPMI),
Williamsburg, VA, 2009


Poster at the Cardiac Physiome Workshop, Cambridge "Towards 
Personalised Simulation of Cardiac Function and Remodelling in 
Tetralogy of Fallot"  (Authors: Mansi, T., Sermesant, M., Delingette, 
H., Ayache, N.)

September 2009

T. Mansi, S. Durrleman, B. Bernhardt, M. Sermesant, H. Delingette, 
I. Voigt, P. Lurz, A. M. Taylor, J. Blanc, Y. Boudjemline, X. Pennec, and 
N. Ayache: A Statistical Model of Right Ventricle in Tetralogy of Fallot for 
Prediction of Remodelling and Therapy Planning, Proc. of Medical 
Image Comp. and Comp. Assisted Intervention (MICCAI'09), 
volume 5761 of Lecture Notes in Computer Science, London, 
UK, pages 214-221, September 2009. 
Springer. http://www.inria.fr/


Invited paper submitted to EMBC 2009, the 31st IEEE Engineering in 
Medicine and Biology Conference "The Neighbourhood Graph for 
Clinical Case Retrieval and Decision Support within Health-e-Child 
CaseReasoner"  (Authors: Tsymbal, A., Zhou, S.K., Huber, M.)
 Link: http://lwa09.informatik.tu-darmstadt.de/pub/WM/WebHome/fgw


Int’l Conf. Medical Image Computing and Computer Assisted 
Intervention, (MICCAI'09), London, UK "Personalized Pulmonary 
Trunk Modeling for Intervention Planning and Valve Assessment 
Estimated from CT Data"  (Authors: Vitanovski, D., Ionasec, R., 
Georgescu, B., Huber, M., Taylor, A., Hornegger, J., Comaniciu, 


R. Ionasec, I. Voigt, B. Georgescu, Y. Wang, H. Houle, J. Hornegger, 
N. Navab, D. Comaniciu: Personalized Modelling and Assessment 
of the Aortic-Mitral Valve Coupling from 4D TEE and CT, Int’l Conf. 
Medical Image Computing and Computer Assisted Intervention, 
(MICCAI'09), London, UK, 2009, Best Poster Session Award


Vitanovski D, Ionasec RI, Georgescu B, Huber M, Taylor AM, 
Hornegger J, Comaniciu D. Personalized pulmonary trunk
modelling for intervention planning and valve assessment 
estimated from CT data. Med Image Comput Comput Assist 
Interv Int Conf. (MICCAI) 2009; 11(Pt1):17-25



Sim-e-Child a FP7 STREP

Sim-e-Child a FP7 STREP

Sim-e-Child a FP7 STREP

Sim-e-Child a FP7 STREP